Miljöpåverkan
Efedrin (vattenfritt)
Miljörisk:
Risk för miljöpåverkan av efedrin (vattenfritt) kan inte uteslutas då ekotoxikologiska data saknas.
Nedbrytning:
Det kan inte uteslutas att efedrin (vattenfritt) är persistent, då data saknas.
Bioackumulering:
Efedrin (vattenfritt) har låg potential att bioackumuleras.
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Detaljerad miljöinformation
Environmental Risk Classification
Predicted Environmental Concentration (PEC)
PEC is calculated according to the following formula:
PEC (μg/L) = (A*109*(100-R))/(365*P*V*D*100) = 1.37*10-6*A(100-R)
PEC = 0.019 μg/L
Where:
A = 140.0467 kg (119.2024 kg ephedrine hydrochloride and 20.8443 kg ephedrine sulfate (total amount API in Sweden year 2021, data from IQVIA). (Ref. 1)
R = removal rate = 0% (no data available)
P = number of inhabitants in Sweden = 10*106
V (L/day) = volume of waste water per capita and day = 200 (ECHA default) (Ref. 2)
D = factor for dilution of waste water by surface water flow = 10 (ECHA default) (Ref. 2)
Ecotoxicological studies
No ecotoxicological data available.
Degradation
No degradation data available.
Bioaccumulation
Log D = -0,75 at pH 7.4 which justifies use of the phrase “Ephedrine has low potential for bioaccumulation”. (Ref. 3)
References:
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Data from IQVIA ”Consumption assessment in kg for input to environmental classification v1 - updated 2022 (data 2021)”.
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ECHA, European Chemicals Agency. Guidance on information requirements and chemical safety assessment. Ver 2.1, 2011.
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http://www.chemspider.com/Chemical-Structure.8935.html?rid=9a7d6c9a-7095-4663-804d-82a4baee7acd#acdLabsTab