Miljöpåverkan
Adrenalin
Miljörisk:
Risk för miljöpåverkan av adrenalin kan inte uteslutas då ekotoxikologiska data saknas.
Nedbrytning:
Det kan inte uteslutas att adrenalin är persistent, då data saknas.
Bioackumulering:
Adrenalin har låg potential att bioackumuleras.
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Detaljerad miljöinformation
Environmental Risk Classification
Predicted Environmental Concentration (PEC)
PEC is calculated according to the following formula:
PEC (µg/L) = (A * 109 * (100-R)) / (365 * P * V * D * 100) = 1.37*10-6 * A(100-R)
PEC = 0.0036 µg/L
Where:
A = 26.5047 kg (total sold amount API in Sweden year 2021, data from IQVIA)
(26.4977 kg (adrenaline tartrate) + 0,0070 kg (adrenalin)). (Ref. 1)
R = 0% removal rate (due to loss by adsorption to sludge particles, by volatilization, hydrolysis or biodegradation).
P = number of inhabitants in Sweden = 10*106
V = 200 L/day (volume of wastewater per capita and day, ECHA default). (Ref. 2)
D = 10 (factor for dilution of waste water by surface water flow, ECHA default. (Ref. 2)
Ecotoxicological studies
No ecotoxicological data available.
Degradation
Abiotic degradation
As no data is available, the following summary phrase is chosen.
The potential for persistence of adrenaline tartrate cannot be excluded, due to lack of data.
Bioaccumulation
Partitioning coefficient:
Log P = -2,59 (Ref. 3)
Summary phrase:
Since Log P < 4 the substance has low potential for bioaccumulation
References:
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Data from IQVIA ”Consumption assessment in kg for input to environmental classification updated 2022 (data 2021)”
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ECHA, European Chemicals Agency. 2008 Guidance on information requirements and chemical safety assessment. http://guidance.echa.europa.eu/docs/guidance_document/information_requirements_en.htm
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Hazardous Substances Data Bank (HSDB). Hazardous Substance Data Bank number: 4289. https://pubchem.ncbi.nlm.nih.gov/source/hsdb/4289